Abstract: For the problems of loud noise, strong vibration and the steaming and smoking from the packing box with high axle temperature during the trial production and running for the fire pump of tankfarm in Ningbo Daxie Island, the natural frequency of centrifugal pump and the vibration frequency of pipelines were comparatively analyzed by using the CAESAR Ⅱ software. The analysis result indicated that the vibration frequency of the pipelines near outlets of the six pumps was much closer to the centrifugal pump's natural frequency because of flexible expansion joints that were installed at outlets of the pumps, which led to the resonance of the centrifugal pumps and the pipelines connected their inlets and outlets. So the suggestion of taking corresponding measures in the initial design stage to avoid the happening of similar problems was put forward.