Abstract: The pour point depressant injection is a physical chemistry method used to modify oil's rheology at low temperature. The paper systematically introduces the process research and application status quo of pour point depressant injection for the waxy crude oil's transportation from the selection and formalas, treatment condition, application method, complete facilities, and injection effect, and meanwhile, explores some problems existed in the research and application of pour point depressant, objectively evaluates the oil transportation process under the condition of pour point depressant injection, and forecasts the developing trend of oil transportation process of pour point depressant injection.