Abstract: GY-3 depressant is added to Jingan crude oil and Wuqi crude oil individually and on-site test is made in Jingma pipeline. By analysis of modified transport process coefficient, it is thought that an optimum depressant injection rate is 50 mg/l and optimum treatment temperature is 60℃. After economical comparison and analysis to the two plans: heating transport and depressant transport, it is considered that depressant transportation can not only realize optimum station configulation, but also reduce pipeline construction engineering cost. It has an evident economic benefit.