Abstract: Application test of FLOXS drag reducer in partial section of Gela Oil Product Pipeline has been carried out. Through comparison and analysis on testing data, it is pointed out that an evident drag reduction result is obtained, meanwhile closing intermediate station and reducing the running equipment at injection station; but varying degrees of shear exists at valves, such as gate valves and bends, which effects on drag reduction result. The article also put forward a proposal that straight pipe section and spherical valve shall be equipped at the points with bends in the design of non-heating operation process for overall pipeline depressant transportation in the days to come.