Abstract: Pipelines often go through the lonely zones, in order to make pipelines operate safely, the operating condition must constantly be monitored, corresponding operation parameters, such as temperature, pressure and earth potential and so on, must be acquired timely, and have it transmit to dispatching center to be analyzed, the pipeline data telemetry system is used for completing these work. Taking 486 industry control computer as a master computer with PASCAL programmed, LY-MCU-552 monolithic processor as a sub-computer with MCS-51 assembly language programmed, the system runs in UCDOS 5.0 operating system. The system has run for half a year in a good operating condition.