Abstract: Hydrogen embrittlement of metal pipelines can be avoided if a polyethylene pipeline is adopted for hydrogen transportation.However, few studies are conducted on the evaluation of compatibility between hydrogen and polyethylene pipeline material, and no systematic research is performed on the lifetime prediction of polyethylene pipelines in a hydrogen environment. In order to predict the effect of hydrogen on the lifetime of polyethylene pipelines, the influence of hydrogen on the performance of polyethylene pipelines was analyzed. Meanwhile, the research progress of the mainstream methods and models for the lifetime prediction of polyethylene pipelines was reviewed, and the lifetime prediction methods used for polyethylene pipelines in the hydrogen environment were discussed. The results show that hydrogen does not have a significant impact on the mechanical properties and permeability of polyethylene pipelines, but the slow crack growth behavior of polyethylene pipelines will be affected in a long-term hydrogen environment, which will affect the service lifetime of polyethylene pipelines. Moreover, a prospect was made for the lifetime prediction method of polyethylene pipelines in the hydrogen environment, as well as its development direction, so as to provide a reference for accelerating the application of non-metallic pipelines in hydrogen transportation.