Abstract: In order to improve the safety of outdoor natural gas stations and detect the natural gas leakage in the process area of the stations in time, a laser gas leakage monitoring system was designed according to the principle of absorbing the methane spectrum with laser, and a leakage monitoring method with high reliability and real-time that is applicable to the gas stations of West-East Pipeline was explored. Based on the long-term tracking of field application effect, the feasibility of application and popularization of the system was studied by comparison and observation. The results show that the laser gas leakage monitoring system can detect the gas leakage at natural gas stations more accurately from the levels of principle and application, and solve the problem of micro-leakage which cannot be automatically detected by the original technology, which reduces the potential safety risks of the natural gas stations and further lays a theoretical foundation for large-scale application in gas pipeline network in the future.