Abstract: According to the concept of intelligent pipeline network and the current status of pipeline enterprises, it was put forward that Digital Twin was the basic method and theoretical basis to realize the intelligent pipeline network. Thereby, based on the theory and the five-dimensional model of Digital Twin, a Digital Twin model of pipeline, including the physical pipeline, the virtual pipeline, the pipeline service system and the pipeline twin data, was constructed, and the connotation of the model, the relationship between various elements, the operation mechanism and the concrete application of key technologies such as cloud computing, big data, artificial intelligence and Internet of Things, were elaborated. In addition, the interaction and fusion between the physical and the virtual pipeline was analyzed, and the application of the pipeline Digital Twin model in the pipeline design, construction, operation, maintenance and other scenarios was discussed. By applying the Digital Twin in the full life cycle of pipeline, the resource allocation was optimized and the level of safety pre-warning was enhanced through data sharing, information visualization and intelligent analysis, with the decision-making ability improved and supports provided for the informatization and intelligent transformation of pipeline industry.