Abstract: Natural gas stations are the key objects of gas leakage monitoring due to the various types of pipeline equipment and a large number of sealing points in them. Considering the shortcomings of traditional gas sensor, such as small detection range, low precision and high false alarm rate, a cloud-based laser gas sensor was proposed, which can realize the three-dimensional gas leakage monitoring of natural gas station, an "optical transceiver + optical cable" based data transmission system was designed according to the process conditions of the stations and the sensor data communication protocol, and an early warning monitoring terminal was developed on the ForceCon configuration software platform with consideration to the monitoring requirements of the stations. The above three parts together constitute the laser scanning gas monitoring system for the natural gas station, which is used in a compressor station of China-Kazakhstan Gas Pipeline. The results show that obvious micro-leakage often occurs in the filtration and separation area and the air-cooling area of the station, and it is related to the operation time of the equipment. Generally, the monitoring result is in line with the actual situation of the compressor station, and the system is of good reliability.