Abstract: The key equipment of oil and gas pipelines is the important treasure of a country because they are related to national energy security. For many years, the key equipment has been imported, which become a bottleneck restricting the high-quality development of oil and gas industry in China. Thus, great attention was attracted from the CPC Central Committee and the State Council to localization, and it was decided to fully guard against and mitigate the risk of "stranglehold" through independent research. With the powerful support of the National Energy Administration and China Machinery Industry Federation, CNPC launched the localization work for equipment in oil and gas pipelines in 2007, set up two batches of major projects of science and technology localization, cooperated with 35 domestic manufacturers. As a result, a major breakthrough was made in the localization of 6 kinds of key equipment, such as compressor unit, oil pump set and valve, which breaks the foreign monopoly, ensures the independence and controllability of oil and gas energy, and further promotes the development of domestic equipment manufacturing to the high end.