Abstract: In the present study, hydrate slurry transportation technology of multiphase pipeline system was furter explored.LedaFlow software was used to calculate the injection amount of inhibitor and simulate the multiphase transportation of hydrate slurry. The parameter optimization module of LedaFlow was used to calculate the optimal injection amount of inhibitor, and its hydrate transportation module was used to simulate the transportation of hydrate slurry. According to the simulation results, the flow laws of hydrate slurry in the pipeline were analyzed and the application of LedaFlow to hydrate slurry flow assurance was preliminarily explored so as to provide the reference for the flow safety assurance of hydrate in gas-condensate pipelines.