Abstract: Inclined drilling, as a commonly-used investigation technology, is rarely used to carry out the investigation on the non-excavation crossing of oil and gas pipelines. Directional drilling and drilling and blasting tunnel are the main non-excavation crossing patterns of oil and gas pipelines. If the geological conditions of crossing area can be figured out by means of inclined drilling, it will be helpful to increase the success rate of non-excavation crossing. Therefore, it is necessary to study the feasibility to apply the inclined drilling investigation in the field of non-excavation engineering. And the practical application indicates that inclined drilling can cooperate with conventional drilling very well to deal with the geological investigation difficulties of engineering investigation effectively. The investigation data obtained through inclined drilling is authentic, credible, accurate and irreplaceable, and it increases the investigation level of oil and gas pipeline engineering greatly. And even in some special pipeline engineering investigation projects, it plays a great role which can not be replaced by the conventional drilling. The survey and researches show that the equipments and technologies used in inclined drilling is applicable to the investigation of non-excavation crossing pipeline engineering.