Abstract: At present, the remote control systems for long-distance crude oil pipelines have been well developed, but the researches on automatic protection of pipeline communication system interruption are insufficient. To develop protection systems for stations and valve chambers along the Shikong-Lanzhou Crude Oil Pipeline, present communication systems and relevant interruptions of the Shikong-Lanzhou Crude Oil Pipeline have been reviewed to highlight major risks in interruption of the communication system for the pipeline. In addition, countermeasures and relevant guidelines for different interruptions of the communication systems have been proposed in accordance with functions of such stations and hydraulic analysis results from the perspective of pipeline operation. As for interruption protection of pipeline communication system, different interruptions have been classified, summarized and generalized to highlight concepts and methods for logics of communication interruption protection. Relevant tests for the protection programs show that the newly developed system can effectively guarantee safe operation of the pipeline.