Abstract: To identify impacts of temperatures and pressures on displacement development, experimental principles and microscopic processes of the natural gas hydrate development involving CO₂ displacement are investigated. Through contrast experiments and by using independently designed experimental devices, impacts of temperatures, pressures and other thermodynamic factors on displacement efficiency and rate are analyzed under temperatures of 274.15 K, 276.15 K, and 278.15 K and pressures of 3.5 MPa, 3.85 MPa and 4.0 MPa, respectively. The results show that both temperature and pressure have significant impacts on displacement performances - impacts of temperatures are higher than that of pressures. Under designated experimental conditions, higher displacement temperatures and pressures may lead to higher displacement rates and better displacement performances. The research results may provide technical guidance for commercial development of natural gas hydrates and promote application of displacement techniques in relevant development operations.