Abstract: At gas compressor stations and valve chambers along the Sichuan to Eastern China Gas Pipeline, the integrated welding globe valves are commonly used as the root valves at the time of pressure or gas sampling. However, since commissioning, minor leakage has frequently occurred at valve stem. If not treated timely, the continuous leakage will cause explosion, fire and other accidents. Against the leakage in gas compressor stations along the Sichuan to Eastern China Gas Pipeline, the leakage stoppage technology under pressure without shutdown is used when valve replacement is unacceptable at early stage of operation. Through the investigation of field leakages, special fixtures are designed and manufactured, and have been effectively used in the leakage stoppage under pressure in case of leakage of pressure gauge root valve simulated in the laboratory. Practical application has proved that the leakage of integrated welding globe valve stem during gas transmission is addressed successfully.