Abstract: At present, CFD commercial software is to put on and a lot of applications, it has become a very important tool in the research and development of oil & gas storage and transportation engineering field. This paper presents the application status of CFD in the field of oil & gas storage and transportation engineering and introduces its basic principle, working process and the calculation result which is displayed and output through the CFD. Besides, the application and achievements made by CFD in three aspects including different operating methods, equipment and its attachment, and the safe operation of pipeline are discussed. Taking the numerical simulation of the flow field of gas-solid two-phase flow in reduced diameter pipe performed by CFD commercial software CFX which is the first software that has passed the ISO9001 quality certification as an example, this paper analyzes the features of flow field of gas-solid two-phase flow and the erosion of particles to fully display the simulation process of CFX, which is of great practical meaning for the further and effective application of CAF technology in the field of oil & gas storage and transportation engineering.