Abstract: This paper, based on the construction of multi-gas sources component equilibrium calculation model in line with real working conditions, takes quality indices of raw gas in natural gas processing plant as objective function, sets up an optimized model to search solutions and finally get operational parameters of pipeline network under the condition of sound pipeline network running constraints and quality indices for the raw gas in gas processing plants. The field cases show that optimized dispatch model for gathering pipeline network can represent the differential gas quality of gas source locations, meet the needs of the natural gas processing plants for raw gas quality, and enable the calculation results to reflect gas quality status in the pipeline network, faithfully and accordingly ensure steady running of purification units. The model, if applied in the real pipeline networks, will provide important basis to the production/operation dispatch of the pipeline networks.