Abstract: Polystyrene-polymethylmethacrylate composite polymer nano-materials are synthesized, of which the polymethylmethacrylate as the surface component further reacts with excessive amidogens in the alkyldiamine methanol solution to form amine-modified polymer nano-material DRA for gas pipeline. Modern instruments are used to analyze chemical structure of the material. It consists of uniformly distributed polymethylmethacrylate spherical nano-particles, with a layer of dodecyl diamine molecule film on the surface and average grain size of 150 nm. Nano-particles can "fill in" rough uneven surfaces of the pipe wall and reduce the roughness with the drag reduction rate of 9%. Synergism of amine groups densely distributed on the nano-particle surface enhances corrosion inhibition performance of nano-materials with an inhibition efficiency of greater than 85%. Therefore, the material can provide the drag reduction and corrosion prevention to the gas pipeline so as to quickly increase throughput under the premise of ensuring pipeline operation safety.