Abstract: The study in this paper serves geological data of a region suiting to construct underground gas storage in aquifer as the background. Based on theory of seepage and numerical simulation, the changing characteristics of reservoir pressure and volume of natural gas bubble in reservoir, the affects of structural characteristics of reservoir and heterogeneity of reservoir on the gas injection results, and that of gas injectionproduction scheme on the results of gas injection-production are all investigated. The results show that the pressure hysteresis appeared in the process of gas injection-production. For the multi-layered aquifer, different gas storages should be built in each aquifer. Swept efficiency can be raised by using foam as gas displacement front in the process of gas injection. Expulsion mechanism of gravity should be used in the process of gas injection. The appropriate gas injection system can be used to improve the storage capacity. Geological fault or mutual contact zone of different faults is the dangerous zone of gas leakage.