Abstract: Taking Rizhao-Yizheng Crude Oil Pipeline and its auxiliary projects as an example, safety pre-assessment on its main risk conditions is executed for the designed pipeline: the hazard levels in Rizhao Pump Station, intermediate station, Yizheng Pump Station and all assessed units in stations are Grade Ⅲ, which belong to the lower risk levels; the risk in most of pipe sections in Jinji Valve Chamber-Yizheng Pump Station is in high risk areas, while the risk of other pipe sections is in moderate risk areas, Based on the results of risk assessment, the corresponding control measures are proposed, recommendations are made from procurement, construction, commissioning, operation and other aspects of work, aiming at lowering the overall safety risk of the pipeline to an acceptable level of risk.