Abstract: Taking the construction of First West-to-East Gas Transmission Pipeline Project as an example, problems existed in high-power frequency-variable generator-driven compressor are analyzed and relative solutions are presented.For external cycling cooling water system, measures in anti-frost.purity of water and optimization of process design are put forward; for venting of filter chamber, methods for optimized ventilation and temperature control are put forward; for compressed air system, the measure to install drying equipment is presented and for lubricant system, measures to optimize power supply and startup procedure in winter are provided.