Abstract: Natural gas produced in Sichuan and Chongqing areas is characterized by high H₂S and CO₂ content, and in the light of this problem, corrosion mechanism of H₂S and CO₂ and physical properties of several desiccants are researched aiming at taking effective measures to control the corrosions.Taking Longmen-Zhongxian Gas Ⅰ ransmission Pipeline as an example, comparison and analysis on the feasibility for methanol.MEG and TEG as desiccants of the pipeline are made from technology, economy and corrosion control.It is pointed out that MEG is a good desiccant with low cost.which can inhibit H₂S and CO₂ corrosion to a certain degree.Thus MEG is recommended as an effective desiccant for Longmen-Zhongxian Gas Transmission Pipeline.