Abstract: Slack flow happens at the peak of the uneven sections of pipelines, while overpressure occurs at the lowest point. Further more, when shuts down the pipeline, the static pressure will be higher in some positions of the pipelines and contamination will be increased. Some problems encountered in constructing China West Products Pipeline are researched and different control modes are analyzed for West Products Pipeline in different slope segments. The influence on contamination forming made by different factors is also analyzed. The factors are as follows: dynamic optimization control methods of regulating valve in pressure-reducing station located in the slope segments of West Products Pipeline, unique feature of hilly pipelines and running states. Combined with the characteristics of the multi-products pipelines constructed and under construction in mountainous areas, some analyses are made for the application. It is considered that simulation and comparison shall be made to the influence of different running modes, slope terrains and the design of pipeline hydraulic steering systems on the forming of contamination for the purpose of finding a safe and economic running control model mode.