Abstract: In the light of the problems in high fuel consumption, short fuel replacement period and poor lubrication effect in 4 diesel gas compressor sets in ShanWu initial station, the necessary lubrication to the motor is urgent. The author considers that the best solutions to this problem are to use gas-fired engine oil to substitute Mobil 1100 systemic lubricants. This engine oil can elongate the oil replacement period from 800 hours to 1500 hours and decrease the consumption of lubricant, improve the property of motor and lower the operation cost. It comes to the conclusion that for the lubrication of gas compressor, Shell NGCF001 cylinder lubricant can effectively lower the lubrication cost compared to Mobil 1100 systemic lubricants.