Abstract: The viscosities of waxy crudes beneficiated by pour point depressants (PPD) may vary after the pump shear or pipe flow shear. The only way for controlling these viscosity variations is to measure the viscosities by the simulation experiments before, which are quite time-consuming for long distant pipelines. A method for predicting the viscosity variations during pipelining is presented in this paper based on the model for predicting shear effect on the viscosity of PPD-beneficiated waxy crudes and the model for predicting nonviscosity of waxy crudes as a function of temperature and precipitated wax. The viscosities of four kinds of PPD-beneficiated waxy crudes during pipelining are predicted according to the presented prediction method. The predicted viscosities fit measured viscosities well with an absolute average deviation of 11.5% for all 44 data. The comparisons between the measured or predicted viscosities during pityelining and the viscosities obtained in the standard PPD evaluation experiment show that the PPD evaluation for the practical application should take shear effect into consideration. The achievements in this paper bring forward a way to evaluate quickly the PPD effect during pipelining.