Abstract: The method to stabilize underwater pipeline with pile-support structure has the features in wide availability, heavy loading capacity and low construction cost.Taken the pipeline stabilization in Tangbai River crossing as an example, the comprehensive analysis on this stabilization method of pipeline has been made.It is pointed out that the pile-support structure can effectively fix underwater pipeline, and by proper adjusting the interval of piles and pile diameter, the crossover and/or crossing distance can be reduced.This method can effectively ensure the safe operation of crossover and/or crossing pipelines.