Abstract: Introduces an application practice of a new generation of drag reducer (Liquid Power^TM) in Mabianzhou-Guangzhou pipeline. Using two main pumps in parallel and injecting certain amount of Liquid Power^TM makes the pipeline realize a throughput of 10×10⁶ t/a. It is applicable both in technology and economy. Compared with the reforming plan without adding drag reducer, it can save primary investment and some operational cost, thus obtain an evident economic benefit.