Abstract: Limitations of PPD comprehensive heating treatment technology and special effects of nanophase material for waxy oil pipelines are summarized and advantages of nanotechnology applied in reducing set point and viscosity of waxy oil for pipeline transportation are discussed. Field applied tests to modify waxy oil with nanophase material in Qian' an-Baodi Commercial Pipeline and Baodi-Baodi Pilot Scale Test Loop were carried out.Resultsshowed that nanophase material modifier can be involved in the course of wax's crystallization and affects wax-crystal structure, which makes the intensity of interior structure of the low-temperature oil weaker and aging stability under dynamic and static states better. Utilization of nanophase material effectively improves low-temperature flow capacity of waxy oil and the effect of the material in reducing set point and viscosity of waxy oil is much better than that of traditional chemical PPD. Nanophase material can be used to realize safety transportation of waxy oil with economic energy.