Abstract: This paper describes concretely the technical reform items of oil-gas-water comprehensive treatment laboratory of Shengli Oilfield, and lists 5 achievements in scientific experiment and study by the reformed laboratory. Actual application shows that the reformed laboratory realizes test medium simulation, test process flow universalization, test process automatization and measurement technique modernization depending on the reformed laboratory. It is considered that the laboratory with high level of automatic control and advanced technology will effectively promote the study achievements to practicality.